Confocal Clarity Upgrade (AUROX)

by Gergely Balogh

AUROX

Aurox Ltd was established in 2004 to commercialise and build upon pioneering work from the Scanning Optical Microscopy Group at the University of Oxford, Department of Engineering Science.

A leader in the design and manufacture of innovative optical imaging equipment, Aurox has received multiple business and technology awards including, the Queen’s Award for Enterprise, the Institute of Physics (IOP) Innovation award and the R&D100 award.

Aurox’s leading product is the Clarity Laser Free Confocal (LFC) unit, which is based on the award winning Aurox SD62; previously sold by Andor as the Revolution DSD and by Zeiss as the Vivatome. The Clarity is the first in a portfolio of new second generation technology products under development by Aurox. This same Aurox technology is used by 3DHistech in their slide scanner product and by Zeiss in their SmartProof5 materials product.

The Clarity revolutionary design delivers affordable confocal microscopy to a wider user community through its ability to attach to any conventional microscope and to provide high quality 3D images to be acquired in real time.

LASER FREE CONFOCAL

AUROX Clarity LFC

The Aurox Clarity is a laser free confocal device delivering extraordinary imaging performance. It’s compact patented optical design and laser-free operation, provide for ease of retrofit to an existing fluorescence microscope, or addition to most new models currently available. The benefits are an affordable confocal device for your own laboratory, eliminating the need to use core facilities.

Key features of Clarity LFC:

  • Laser free confocal
  • Full spectrum (370 – 700 nm)
  • Excellent confocality
  • Unique single camera design with large field of view
  • High throughput
  • Highly cost effective
  • A range of interchangeable filter cubes
  • Real-time control and viewing (up to 50 frames per second)
  • Suitable for fixed and live specimens

The Aurox Clarity is a laser free confocal device delivering extraordinary imaging performance. It’s compact patented optical design and laser-free operation, provide for ease of retrofit to an existing fluorescence microscope, or addition to most new models currently available. The benefits are an affordable confocal device for your own laboratory, eliminating the need to use core facilities.

AUROX Clarity HS

The Aurox ClarityHS is the next generation in laser free confocal instruments using the Aurox patented structured illumination spinning disc design.

Structured illumination achieves significantly greater light through the spinning disc compared with a Nipkov pinhole design. As a result, structured illumination affords higher resolution, higher quality confocal images.

The HS of ClarityHS stands for High Speed which comes from its fast, up to 100 frames per second full frame video capture rate. This fast imaging ability makes the ClarityHS ideal for higher resolution 3D time lapse imaging.

The ClarityHS can record comparable images to laser scanning confocal microscopes, faster and from an easy to use and more affordable device; both in terms of initial purchase price and on-going maintenance.

The ClarityHS has been designed to be added on to your existing microscope, thereby upgrading your microscope to be confocal.

Key features of Clarity HS:

  • 100 frames per second fast full frame video capture
  • Easy upgrade to your microscope
  • Full 5D confocal microscopy (xyzλt)
  • No maintenance
  • Confocal and Widefield modes
  • Structured illumination disc
  • A wide range of interchangeable filter cubes available
  • Fast, easy to use Visionary software