SUPERNOVA‑100 – Miniature Two‑Photon Imaging System for Freely Moving Animals
Revolutionizing In Vivo Neuroscience
The SUPERNOVA‑100 is a compact, high‑performance imaging system that delivers benchtop‑grade two‑photon resolution in freely moving animals. Weighing just ~2.6 g and powered by advanced femtosecond laser delivery, it enables researchers to visualize neurons and synapses in real time—ushering in a new era of behavioral neuroscience
Free-Moving Animal Imaging
Key features os Transcend Supernova-100
Subcellular Resolution
Achieve crystal-clear imaging of dendrites, spines, and synapses using either cranial windows (~800 µm) or implanted GRIN lenses.
Lightweight & Wearable
The miniature headpiece (~2.6 g) minimally impacts animal behavior, preserving naturalistic conditions.
Continuous, Long‑Term Recordings
Designed for low photobleaching, it supports uninterrupted imaging sessions over 24 hours and extends to repeated multi-session studies across months with <10 µm displacement.
Volumetric Imaging with ETL
Integrated electrical tunable lens enables rapid z‑sectioning, capturing activity across multiple cortical layers in 3D.
Robust Performance Metrics
Options of headpieces with 0.65–1.38 µm lateral resolution, axial precision of 3.7–23 µm, and FOV up to 1.33 mm are available.
Research Applications
- Map neuronal network dynamics and optogenetic manipulation effects in the dorsomedial PFC
- Visualize neurotransmitter signaling such as ACh3.0 during behavior
- Investigate sensory circuits during itch or locomotion studies
- Track the same cellular populations longitudinally during development or disease progression
These powerful applications stem from SUPERNOVA‑100’s ability to replicate the quality of a benchtop two‑photon system in freely behaving subjects.
Discover the future of in vivo imaging.
Request a quote, discuss custom configurations, or schedule a live demo.
Contact us today to explore how SUPERNOVA‑100 can elevate your neuroscience research.